What is Down Syndrome?

1, Down's syndrome is a trisomy 2 1- syndrome, also known as congenital stupidity or Down's syndrome, which is a disease caused by chromosome abnormality (one extra chromosome 2 1). 60% of the children miscarried in the early fetus, and the survivors had obvious mental retardation, special face, growth and development obstacles and multiple deformities.

2. The child has obvious special facial signs, such as wide eye distance, low nasal root, small eye fissure, oblique eye, epicanthus, small external ear, fat tongue, frequent spitting and drooling. Short stature, smaller head circumference than normal people, short head back and forth diameter, flat head pillow. The neck is short and the skin is slack. Bone age often lags behind age, delayed teething and frequent dislocation. Hair is soft and less. The anterior fontanel closed late, and there may be a third fontanel in the occipital midline. The limbs are short, the joints can be excessively bent due to ligament relaxation, the fingers are thick and short, and the middle phalanx of the little finger is underdeveloped, which makes the little finger bend inward, the phalanx is short, and the trigeminal point of the palm shifts to the distal end. Palm prints and sandal feet are common, and about half of children with big toes are arched dermatoglyphics.

3. Sleepiness and eating difficulties are common, and their mental retardation is gradually obvious with age. IQ 25 ~ 50, delayed motor development and sexual development.

4. Male Down's baby will not have fertility until adolescence. A female Down's baby will have menstruation when she grows up and may give birth to a child.

5. Children are often accompanied by congenital heart disease and other malformations. Because of their low immune function, they are prone to various infections, and the incidence of leukemia is 10 ~ 30 times higher than that of the general population. If you live to adulthood, you will often have symptoms of Alzheimer's disease after 30 years old.