Why doesn't Queen Tang Gaozong have children?

Queen Wang was born in a big family and was the daughter-in-law chosen by Emperor Taizong of SHEN WOO. Her appearance and temperament are the best choice. When she married Kim, she seemed to be less than 15 years old. It can be said that she was young and eager for love, and it was impossible to consummate her marriage. You know, after the Queen Wang was put in prison, Li Zhi secretly visited her, which shows that they have feelings. The Queen Wang was twenty-four or five years old when she was killed by Wu Mei. After ten years of marriage, she has no children. It is definitely not the problem of Emperor Li Zhi, because other women in Li Zhi have children, and it can only be the queen's own problem.

Of course, some conspiracy theories or film and television works will think that Wu Mei has taken some medicine, but it is actually impossible. Wang married Li a few years ago, and Wu Mei later met Li Zhi. Will Wu Mei know that Wang is her enemy when she gets married and send someone to poison Wang?